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海金沙为海金沙科植物海金沙的成熟孢子。具有清热解毒,利水通淋功能。适用于尿路感染和结石。海金沙及其根可治疗黄疸型肝炎,本品所含咖啡酸有利胆保肝功能。我们从海金沙中分离出单体成分——反式对香豆酸(Trans-p-coumanic acid),分子式:C_9H_8O_3,分子量:164,结构式为HO(?)-CH=CH-COOH。系白色结晶,溶点为210～212℃,稍溶于冷水,能溶于热水、醚和碱液。经药理试验,证实有利胆作用,现报告如下。材料与药品反式对香豆酸(Trans-p-coumanic acid):本所从安徽产的海金沙中提的白色结晶。用时用pH8的5％NaHCO_3配成20mg/ml浓度。
Haijinsha is the mature spore of Haijinsha, a plant of Haijinsha. With heat and detoxification, Lee water Tonglin function. Suitable for urinary tract infections and stones. Haijinsha and its roots can treat jaundice hepatitis. The caffeic acid contained in this product is good for liver function. We isolated the monomer composition trans-p-coumanic acid from Haijinsha, molecular formula: C_9H_8O_3, molecular weight: 164, structural formula HO(?)-CH=CH-COOH. White crystal, melting point 210 ~ 212 °C, slightly soluble in cold water, soluble in hot water, ether and alkali. The pharmacological tests confirmed the beneficial effects of gallbladder. The report is as follows. Materials and Pharmaceuticals Trans-p-coumanic acid: The white crystals of the seaweed produced in Anhui. When used, a concentration of 20 mg/ml was formulated with 5% NaHCO 3 at pH 8.