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采用改良Jourdian法测定了50例肝癌、26例慢性肝炎及肝硬化患者的血清唾液酸含量，并与甲胎蛋白、铁蛋白检测结果进行对比分析。肝癌患者唾液酸高于良性肝病，阳性率分别为82．0％、2尔9％。18例甲胎蛋白阴性的肝癌中有16例其唾液酸阳性。肝癌患者钱蛋白大于300ug／L者占74．0％，良性疾病占57.7％，说明唾液酸在肝癌的辅助诊断，尤其是在普查中有应用价值，且较铁蛋白效果好。
The serum sialic acid levels in 50 cases of HCC and 26 cases of chronic hepatitis and liver cirrhosis were determined using the modified Jourdian method. The results were compared with those of alpha fetoprotein and ferritin. The sialic acid in patients with hepatocellular carcinoma was higher than that in benign liver disease. The positive rates were 82.0% and 2% respectively. Among the 18 cases of AFP negative liver cancer, 16 cases were positive for sialic acid. Patients with hepatocellular carcinoma accounted for 74.0% of those with a blood protein level of more than 300 ug/L, and 57.7% of benign diseases. This suggests that sialic acid has an auxiliary value in the diagnosis of hepatocellular carcinoma, especially in the census, and is more effective than ferritin.