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目的:观察在常规药物治疗基础上,采用黄芪生脉饮与倍他乐克联合治疗舒张性心力衰竭的临床疗效。方法:纳入85例舒张性心力衰竭患者,随机分为对照组40例和观察组45例。2组均予常规药物治疗,同时服用倍他乐克,观察组加服黄芪生脉饮,2组分别治疗28天,观察患者的临床疗效、临床症状评分和6 min步行距离。结果:临床疗效总有效率观察组为93.33%,对照组为77.50%,2组比较,差异有统计学意义(P<0.05)。治疗后,2组心悸、胸闷、乏力、浮肿、口唇紫暗评分均较治疗前有不同程度下降(P<0.05);观察组胸闷、乏力和口唇紫暗评分与对照组比较下降明显(P<0.05)。治疗后,2组患者的6 min步行距离均较治疗前增加(P<0.05),2组间比较,差异亦有统计学意义(P<0.05)。结论:在常规药物治疗基础上,采用黄芪生脉饮与倍他乐克联合治疗舒张性心力衰竭具有积极的治疗作用。
Objective: To observe the clinical efficacy of combining Huangqi Shengmai Decoction with Betaloc in the treatment of diastolic heart failure. Methods: Eighty-five patients with diastolic heart failure were included and randomly divided into control group (n = 40) and observation group (n = 45). The patients in both groups were given routine drug therapy while taking metoprolol. The observation group was given Astragalus Sheng Mai Yin. The two groups were treated for 28 days respectively. The clinical efficacy, clinical symptom score and walking distance of 6 min were observed. Results: The total effective rate of clinical curative effect was 93.33% in the observation group and 77.50% in the control group. There was significant difference between the two groups (P <0.05). After treatment, the scores of heart palpitations, chest tightness, weakness, edema and lip and darkness in the two groups were all decreased to some extent (P <0.05). The scores of chest tightness, fatigue and lip-darkness in the observation group decreased significantly compared with the control group (P < 0.05). After treatment, the walking distance of 6 min in both groups increased compared with that before treatment (P <0.05). There was also significant difference between the two groups (P <0.05). Conclusion: On the basis of conventional drug therapy, the combination of Astragalus Sheng Mai Yin and Betaloc with diastolic heart failure has a positive therapeutic effect.