对不丹传统药用植物乌头属植物 A.orochryseum Stapf 进行研究,分离得到3个新的hetisine-型二萜生物碱 orochrine(1)、2-O-acetylorochrine(2)、2-O-acetyl-7 α-hydroxyorochine(3)和2个已知生物碱氯化阿替新(4)、变绿卵孢碱(5),并用光谱法确定了3个新生物碱的结构。该植物地上部分自然干燥、切碎,用甲醇提取4 The traditional medicinal plant A.orochryseum Stapf from Bhutan was studied and three new hetisine-type diterpene alkaloids orochrine(1), 2-O-acetylorochrine(2), 2-O-acetyl were isolated. -7 α-hydroxyorochine (3) and 2 known alkaloids were used for the chlorination of altenosin (4) and green chlorocystine (5), and the structures of the three new alkaloids were determined by spectroscopic methods. The aerial parts of the plant are naturally dried, chopped and extracted with methanol 4