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结校瘸目前仍为人类一大威胁.每年有800～1000万新病例.300万例病死.受害最严重的是小儿.有报告指出.1982～1992年新病例发生率增加20％.15岁以下儿童儿乎增加40％。与结核病发病同时是耐药菌增加~[1],现将有关文献综述如下。 现 状 过去10年.纽约成人结核耐药菌迅速增多.儿童也同步上升.疾病控制中心(CDC)1994年调查显示.儿童结核病18.9％对1种以上抗结核药耐药~[1].美国于1982～1990年调查.发现耐异烟肼(INH)由9％增至15％,耐利福平(RFP)由3％增至9％.耐INH和RFP由3％增至7％~[2]。还报道多起医院内耐药结棱病暴发。其病死率高达80％~[3]。在新发现的病例中,以移居美国的和15岁以下儿童所
The crippling school is still a major threat to mankind, with 800 to 10 million new cases, 3 million deaths each year, and the most serious victims are children, with a 20% increase in the number of new cases from 1982 to 1992. The 15-year-old The following children increased almost 40%. At the same time with the incidence of tuberculosis is an increase in resistant bacteria ~ [1], the relevant literature are summarized below. In the past 10 years, the number of TB-resistant adults in New York City has risen rapidly, and children have also risen simultaneously. The Centers for Disease Control and Prevention (CDC) survey in 1994 showed that 18.9% of childhood TB were resistant to more than one type of anti-TB drug. [1] From 1982 to 1990, it was found that INH increased from 9% to 15% and RFP increased from 3% to 9%, INH and RFP increased from 3% to 7% 2]. There were also reports of outbreaks of multidrug resistance in the hospital. The fatality rate as high as 80% ~ [3]. Among newly discovered cases, immigrants to the United States and children under 15 years of age