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目的探讨尤瑞克林对进展型脑梗死的治疗效果。方法将117例进展型脑梗死患者随机分为两组,治疗组在对照组治疗基础上,每日应用尤瑞克林0.15PNA加入生理盐水100ml静脉滴注,连用21d,使用尤瑞克林期间不使用血管紧张素转换酶抑制剂。治疗组和对照组在治疗前,治疗后21d进行神经功能缺损程度评定及疗效评定。结果治疗21d后,治疗组神经功能缺损评分为(10.35±3.52)分,明显低于对照组(14.72±4.11)分,(P<0.05);治疗组有效率为87.5%,显著高于对照组的65.6%(P<0.05)。结论尤瑞克林是治疗进展型脑梗死的有效药物。
Objective To investigate the therapeutic effect of urelin on progressive cerebral infarction. Methods 117 patients with progressive cerebral infarction were randomly divided into two groups. On the basis of the treatment of the control group, the patients in the treatment group were treated with intravenous infusion of 100 mg of irinotecan 0.15PNA daily with saline for 21 days, No angiotensin converting enzyme inhibitors. The treatment group and the control group were evaluated on the degree of neurological deficit and the curative effect 21 days after treatment before and after treatment. Results After 21 days of treatment, the score of neurological deficit in the treatment group was (10.35 ± 3.52) points, which was significantly lower than that of the control group (14.72 ± 4.11) (P <0.05). The effective rate of the treatment group was 87.5%, which was significantly higher than that of the control group Of 65.6% (P <0.05). Conclusion Erilecin is an effective drug for the treatment of progressive cerebral infarction.