肾病综合征是临床上治疗比较困难,且容易反复发作的一种儿童常见疾病。晚近,学者们对此病病因和治疗方面的研究,已有显著进展,尤其是应用类固醇及免疫抑制剂以来,使本病的疗效和预后有了相当的改善。我科自1972年以来,应用免疫抑制剂——环磷酰胺治疗曾用类固醇正规治疗多次复发的肾病综合征病儿,获得了满意的效果。现报道如下: Nephrotic syndrome is clinically difficult to treat and prone to recurrent episodes of a common childhood disease. Recently, scholars have made significant progress on the etiology and treatment of the disease, especially since the application of steroids and immunosuppressive agents, so that the efficacy and prognosis of the disease has been considerably improved. Our department since 1972, the application of immunosuppressant - cyclophosphamide once steroid treatment of children with multiple relapse of nephrotic syndrome, obtained satisfactory results. Reported as follows now: