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目的 研究帕金森病MRI与临床的关系。方法 对43例帕金森病患者进行MRI检查,对MRI异常组和正常组的起病年龄、病程、运动和认知功能进行比较,选Hoehn和Yahr分期以及MMSE和WAIS-RC分别作为运动和认知功能的判定标准。结果 28例MRI表现异常,其表现为脑萎缩及侧脑室周围T2高信号改变,MRI异常组和正常组相比,平均起病年龄、病程、运动和认知功能均有统计学差异,P<0.05。结论 MRI的异常表现与临床相关。
Objective To study the relationship between Parkinson’s disease MRI and clinical. Methods Forty-three patients with Parkinson’s disease were examined by MRI. The age, course of disease, motor and cognitive function of patients with abnormal MRI group and normal group were compared. Hoehn and Yahr staging, MMSE and WAIS-RC Judgment of the function of the standard. Results The MRI findings of 28 patients were abnormal. The changes of brain atrophy and hyperintensities of T2 around the lateral ventricle were observed. Compared with the normal group, the average onset age, course of disease, motor and cognitive function of MRI group were significantly different (P < 0.05. Conclusion The abnormal MRI findings are clinically relevant.