自从1964年Blumberg等发现澳大利亚抗原(乙型肝炎表面抗原,HBsAg)以来,在世界范围内已进行了大量的乙型肝炎病毒(HBV)感染的流行病学研究。有很多研究结果表明,对HBV感染的反应存在着性别差异。这主要表现在以下几个方面: 一、HBsAg的携带率相当多的流行病学调查均发现,HBsAg携带者中男性比女性多见,特别是在年轻成人组更明显。二、抗-HBs的阳性率在很多流行病学调查结果中显示女性比男性抗-HBs阳性率要高。对若干HBsAg阳 Since the discovery of the Australian antigen (hepatitis B surface antigen, HBsAg) by Blumberg et al. In 1964, a large number of epidemiological studies of Hepatitis B virus (HBV) infection have been conducted worldwide. Many studies have shown that there is a gender difference in the response to HBV infection. This is mainly manifested in the following aspects: First, the considerable carrying rate of HBsAg epidemiological survey found that more common in women than in women with HBsAg carriers, especially in the younger adult group is more obvious. Second, anti-HBs positive rate in many epidemiological findings showed that women than men, anti-HBs positive rate is higher. Several HBsAg positive