目的:观察血清肝胆酸在中孕、晚孕和非孕期人群中的阳性率,并探讨其临床意义。方法:用放射免疫法检测人血清肝胆酸。结果:中期孕妇、晚期孕妇、非孕期人群血清肝胆酸阳性率分别为11.7%、31.9%、2.5%。结论:提示血清肝胆酸的检测对于中晚期孕妇有较为重要的临床意义。 Objective: To observe the positive rate of serum heptocholic acid in second trimester, second trimester and non-trimester, and to explore the clinical significance. Methods: Radioimmunoassay was used to detect human hepatocholic acid. Results: The positive rates of serum hepatobiliary acid in mid-term pregnant women, late pregnant women and non-pregnant women were 11.7%, 31.9% and 2.5% respectively. Conclusion: It is suggested that the detection of serum hepatocholic acid has more important clinical significance for the middle and late pregnant women.