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目的:探讨稽留流产应用米非司酮配伍米索前列醇的临床疗效。方法:选择滕州市中心人民医院收治的稽留流产患者1 960例,随机分为观察组和对照组,每组各980例。观察组口服米非司酮配伍米索前列醇;对照组口服己烯雌酚。根据子宫大小行钳刮术或静脉滴注缩宫素,待其自然排出胎儿、胎盘后行清宫术,观察两组清宫情况。结果:观察组流产成功率为91.84%,对照组流产成功率为59.18%,观察组流产成功率明显高于对照组。结论:米非司酮配伍米索前列醇口服能安全有效地终止稽留流产,具有疗效好、出血量少,方法简便、用药剂量小等优点,可减少术后不全流产的几率,避免人工流产综合征的发生。
Objective: To investigate the clinical efficacy of mifepristone with misoprostol in missed abortion. Methods: A total of 1 960 missed abortion patients were selected from People ’s Hospital of Tengzhou City, and randomly divided into observation group and control group with 980 cases in each group. The observation group was treated with mifepristone and misoprostol. The control group was given diethylstilbestrol orally. According to the size of the uterine forceps curettage or intravenous injection of oxytocin to be their natural discharge of the fetus, curettage after the placenta, observe the two groups Qing situation. Results: The success rate of abortion in the observation group was 91.84%, the success rate of abortion in the control group was 59.18%. The success rate of abortion in the observation group was significantly higher than that of the control group. Conclusion: The combination of mifepristone and misoprostol orally can effectively and effectively abort the missed abortion, which has the advantages of good curative effect, less bleeding, simple method and small dosage, which can reduce the chance of postoperative incomplete abortion and avoid abortion Occurrence of the sign.