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目的:探讨直肠癌术后放疗患者膀胱平均受量及直肠受量对放射性膀胱炎及放射性肠炎的影响。方法:收集我院2005年7月至2010年12月收治的直肠癌根治术后给予放疗的患者130例,收集临床因素、病理因素、放疗因素资料,统计放疗后6个月内放射性肠炎、放射性膀胱炎发生情况。结果:放疗因素中,膀胱壁平均照射剂量对放射性肠炎及膀胱炎的发生有显著影响(P<0.05),即膀胱壁剂量越高,副反应发生率越大;当膀胱壁平均剂量达到49.12 Gy时,放射性膀胱炎的发生率显著升高。小肠平均剂量控制在50 Gy以下,其值与放射性肠炎的发生无相关性。结论:直肠癌术后放疗患者膀胱壁平均受量控制在49.12 Gy以下,对减少放射性膀胱炎的发生率有意义。
Objective: To investigate the average amount of urinary bladder and rectal dose after radiotherapy for rectal cancer patients with radiation cystitis and radiation enteritis. Methods: A total of 130 patients undergoing radical radiotherapy for rectal cancer undergoing radical resection from July 2005 to December 2010 were enrolled in this study. Clinical data, pathological data and radiotherapy data were collected. Radiological enteritis and radioactivity were collected within 6 months after radiotherapy Cystitis occurs. Results: In the radiotherapy factors, the mean radiation dose of the bladder wall had a significant effect on the occurrence of radiation enteritis and cystitis (P <0.05). The higher the dose of the bladder wall, the greater the incidence of side effects. When the mean bladder wall dose reached 49.12 Gy When the incidence of radiation cystitis was significantly increased. The mean dose of small intestine was controlled below 50 Gy, and its value had no correlation with the occurrence of radiation enteritis. Conclusion: The average volume of bladder wall in patients undergoing postoperative radiotherapy for rectal cancer is controlled below 49.12 Gy, which is significant for reducing the incidence of radiation cystitis.