手足口病(Hand foot and mouth disease HFMD)是一种常见的传染病,可由多种肠道病毒引起,5岁以下儿童易感。可引起手、足、口腔等部位的疱疹,少数患儿可引起心肌炎、肺水肿、无菌性脑膜脑炎等并发症。少数重症患儿如果病情发展快,会导致死亡。引发手足口病的肠道病毒有20多种,其中以肠道病毒71型(EV71)和柯萨奇病毒A组16型(Cox A16)最为常见[1-2]。据文献报道,自2008年 Hand foot and mouth disease (HFMD) is a common infectious disease that can be caused by a variety of enterovirus infections in children under 5 years of age. Can cause hand, foot, mouth and other parts of the herpes, a small number of children can cause myocarditis, pulmonary edema, aseptic meningoencephalitis and other complications. A small number of critically ill children if the disease develops rapidly, can lead to death. There are more than 20 kinds of enterovirus causing hand-foot-mouth disease, among which enterovirus 71 (EV71) and Cox-A16 are most common [1-2]. According to the literature, since 2008