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目的 探讨兔实验性颈总动脉—颈外静脉动静脉瘘模型建立的可行性。方法 用显微外科技术对5只兔子建立实验性动静脉瘘,并作数字减影血管造影(DSA)观察瘘口附近动静脉发生的血流动力学改变。结果 5只兔颈总动脉与颈外静脉侧侧吻合均一次成功。血管造影清楚显示吻合口近端动脉与近端静脉、近端动脉与吻合口两端静脉、吻合口两端动静脉同时显影,且随着注射进影剂压力的增大,吻合口远端颅内静脉细小属支亦见显影。结论 通过显微血管吻合方法建立兔颈总动脉—颈外静脉动静脉瘘模型切实可行。
Objective To explore the feasibility of establishing experimental model of carotid artery-jugular vein arteriovenous fistula in rabbits. Methods Experimental arteriovenous fistula was established in 5 rabbits by microsurgical technique. The hemodynamic changes of arteriovenous vein in the vicinity of the fistula were observed by digital subtraction angiography (DSA). Results 5 rabbits common carotid artery and external jugular vein anastomosis were successful. Angiography clearly shows proximal anastomotic artery and proximal vein, proximal artery and anastomosis at both ends of the vein, anastomosis at both ends of the arteriovenous simultaneously developed, and with the injection of the injection pressure increases, distal anastomotic fossa Intrauterine small branch also see the development. Conclusion The establishment of rabbit common carotid artery-jugular vein arteriovenous fistula model via microvascular anastomosis is feasible.