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目的分析比较联合枸橼酸钾和坦洛新治疗输尿管下段结石的疗效。方法将92例输尿管下段结石患者随机分为四组:对照组(常规治疗);坦洛新组(常规治疗加用坦洛新);枸橼酸钾组(常规治疗加用枸橼酸钾);联合组(常规治疗加用枸橼酸钾联合坦洛新)各23例,观察4周后分析疗效。结果经过4周的治疗,与对照组比较,联合组、坦洛新组和枸橼酸钾组排石率显著增高(P<0.05),其中联合组排石率优于枸橼酸钾组与坦洛新组(P<0.05)。结论枸橼酸钾联合坦洛新治疗输尿管下段结石可发挥协同作用。
Objective To analyze the curative effect of combining potassium citrate and tamsulosin on the lower ureteral calculi. Methods Totally 92 patients with lower ureteral stones were randomly divided into four groups: control group (conventional treatment); tamsulosin group (conventional treatment plus tamsulosin); potassium citrate group (conventional treatment plus potassium citrate) ; Combination group (conventional treatment plus potassium citrate combined with tamsulosin) in 23 cases, after 4 weeks of observation the curative effect. Results After 4 weeks of treatment, the rate of stone extraction in the combination group, tamsulosin group and potassium citrate group was significantly higher than that in the control group (P <0.05), and the rate of stone removal in the combined group was superior to that in the potassium citrate group Tamsulosin group (P <0.05). Conclusion Potassium citrate combined with tamsulosin treatment of lower ureteral calculi can play a synergistic effect.