论文部分内容阅读
目的 :探讨超声引导下空芯针穿刺活检(ultrasound-guided core needle biopsy,US-CNB)在乳腺肿块诊疗中的临床价值。方法:回顾性分析1 210例患者1 241个乳腺肿块US-CNB的病理资料,并与术后组织病理结果进行比较,评价US-CNB在乳腺肿块诊疗中价值。结果:1 241个乳腺肿块组织中US-CNB病理诊断乳腺癌970例,术后病理组织诊断乳腺癌1 000例,CNB病理诊断乳腺癌的灵敏度为97%,特异度为100%,阳性预测值为97%,阴性预测值为100%,假阴性率为3%,正确指数为0.97,诊断符合率为97.58%。约登指数为0.97,Kappa值为0.975 8。结论 :US-CNB灵敏度高,病理诊断结果与术后病理诊断结果符合率高,且安全有效,对指导乳腺癌的个体化治疗具有重要的临床价值。
Objective: To investigate the clinical value of ultrasound-guided core needle biopsy (US-CNB) in the diagnosis and treatment of breast masses. Methods: The pathological data of 1,241 breast masses from 1 210 cases of US-CNB were retrospectively analyzed and compared with postoperative histopathological findings to evaluate the value of US-CNB in the diagnosis and treatment of breast masses. Results: There were 970 cases of breast cancer diagnosed by US-CNB in 1 241 breast masses and 1 000 cases of breast cancer diagnosed by pathology. The sensitivity and specificity of CNB pathological diagnosis of breast cancer were 97% and 100% respectively. The positive predictive value Was 97%, the negative predictive value was 100%, the false negative rate was 3%, the correct index was 0.97, and the diagnostic coincidence rate was 97.58%. Youden index is 0.97 and Kappa is 0.975 8. CONCLUSION: US-CNB has high sensitivity, high coincidence rate of pathological diagnosis and postoperative pathological diagnosis, and is safe and effective. It has important clinical value in guiding the individualized treatment of breast cancer.