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目的探讨硫糖铝混悬液联合泮托拉唑片治疗高原地区糜烂性胃炎临床效果。方法选取高原地区92例糜烂性胃炎患者依据随机双盲原则分为观察组与对照组。对照组46例给予泮托拉唑片口服治疗,观察组46例在此基础上联合硫糖铝混悬液治疗。对两组患者的临床治疗效果及腹胀、腹痛缓解时间、Hp阴转情况进行记录与分析。结果观察组临床治疗有效率显著高于对照组,观察组腹胀、腹痛缓解情况显著优于对照组,差异有统计学意义(P<0.05);两组Hp阴转率相比,差异无统计学意义(P>0.05)。结论硫糖铝混悬液联合泮托拉唑片对于高原地区糜烂性胃炎患者具有良好的临床治疗效果,可有效改善患者的临床症状,值得推广。
Objective To investigate the clinical effect of sucralfate suspension and pantoprazole tablet in the treatment of erosive gastritis in the plateau area. Methods 92 patients with erosive gastritis were randomly divided into observation group and control group according to the randomized double-blind principle. In the control group, 46 cases were treated with pantoprazole tablets orally, 46 cases in the observation group were treated with sucralfate suspension on the basis of this. On the two groups of patients with clinical treatment and abdominal distension, abdominal pain relief time, Hp negative conversion record and analysis. Results The effective rate of clinical treatment in the observation group was significantly higher than that in the control group. The relief of abdominal distension and abdominal pain in the observation group was significantly better than that in the control group (P <0.05). There was no significant difference in the Hp negative conversion rate between the two groups Significance (P> 0.05). Conclusion Sucralfate suspension combined with pantoprazole tablet has good clinical curative effect on patients with erosive gastritis in the plateau region, which can effectively improve the clinical symptoms of patients and is worth promoting.