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目的:探讨原发性肝癌根治术后病人肺部并发症发生的危险因素。方法:收集2011年3月至2014年2月间因原发性肝癌行肝癌根治术病人120例,根据有无并发症将两组病人分为肺部并发症和无肺部并发症组,对病人的一般情况、术前检查及手术情况设置变量首先用单因素方法筛选与肝癌根治术后肺部并发症相关的危险因素,进一步行多因素logistic分析这些相关危险因素中的独立危险因素。结果:入组病人中术后有25例(20.83%)发生了肺部并发症。单因素分析结果显示肝癌根治术后肺部并发症发生的危险因素有:慢性呼吸道疾病史、术前2周呼吸道感染史、术前白蛋白水平、手术时间、麻醉时间、术中出血量及术后使用镇痛泵(P<0.05)。Logistic分析显示肝癌根治术后肺部并发症发生的独立危险因素为:慢性呼吸道疾病史、术前白蛋白水平及术后使用镇痛泵(P<0.05)。结论:原发性肝癌根治术患者存在术后肺部并发症危险因素,临床工作中对其进行评估可减少或避免发生并发症。
Objective: To explore the risk factors of pulmonary complications in patients with primary liver cancer after radical operation. Methods: From March 2011 to February 2014, 120 patients with primary hepatocellular carcinoma undergoing radical resection of liver cancer were collected. According to the presence or absence of complications, the patients were divided into two groups: pulmonary complication and non-pulmonary complication The general situation of patients, preoperative examination and surgical settings variables First, single factor screening of risk factors associated with pulmonary complications of radical resection of liver cancer, and further multivariate logistic analysis of these related risk factors of independent risk factors. Results: Pulmonary complications occurred in 25 patients (20.83%) after operation. Univariate analysis showed that the risk factors of pulmonary complications after radical operation of hepatocellular carcinoma include the history of chronic respiratory diseases, the history of respiratory infection 2 weeks before operation, the preoperative albumin level, operation time, anesthesia time, intraoperative blood loss and operation After the use of analgesic pump (P <0.05). Logistic analysis showed that the independent risk factors of pulmonary complications after radical operation were the history of chronic respiratory diseases, preoperative albumin level and postoperative analgesia pump (P <0.05). Conclusion: There are risk factors of postoperative pulmonary complications in patients with primary liver cancer who underwent radical resection. Assessment in clinical work may reduce or avoid the occurrence of complications.