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目的进一步探讨微生态制剂在治疗婴幼儿急性腹泻中的临床效果。方法对新疆医科大学第五附属医院儿科2007年1月—2009年10月收住院的急性腹泻患儿388例进行回顾性分析,根据是否加用口服微生态制剂,分为治疗组和对照组,2组患儿均给予常规补液对症治疗,治疗组在此基础上加用口服肠道微生态制剂。对2组患儿治疗效果、病程及平均住院天数、住院费用进行统计学分析。结果对2组患儿的治疗效果、平均住院天数、住院费用进行t检验,经统计学处理后P<0.05,差异均具有统计学意义。提示对急性腹泻患儿进行常规补液对症治疗并配合口服微生态制剂可明显提高治疗效果。结论微生态制剂在治疗婴幼儿急性腹泻中疗效明显,能缩短住院天数、节约治疗费用,降低院内交叉感染,减轻患儿痛苦,故在临床上值得推广。
Objective To further explore the clinical efficacy of probiotics in the treatment of acute diarrhea in infants and young children. Methods 388 cases of acute diarrhea admitted to the Children’s Hospital of the Fifth Affiliated Hospital of Xinjiang Medical University from January 2007 to October 2009 were retrospectively analyzed. The patients were divided into treatment group and control group according to whether oral probiotics were added or not. Two groups of children were given conventional rehydration symptomatic treatment, the treatment group on the basis of the use of oral gut probiotics. Two groups of children with treatment, duration and average length of stay in hospital, hospital costs for statistical analysis. Results The treatment effect, average days of hospitalization and hospitalization of two groups of children were analyzed by t-test. After statistical analysis, P <0.05, the differences were statistically significant. It is suggested that the routine rehydration symptomatic treatment of acute diarrhea children with oral probiotics can significantly improve the therapeutic effect. Conclusions The probiotics are effective in treating acute diarrhea in infants and young children, which can shorten the hospitalization days, save the treatment cost, reduce the cross-infection in the hospital and relieve the pain of children. Therefore, it is worthy of clinical promotion.