Objective:To observe the therapeutic effect of antihyperlipidemic decoction on hyperlipemia. Methods: 77 hyperlipemia patients are selected and randomly divided into two groups. 37 cases in the treatment group received the treatment of antihyperlipidemic decoction, and 40 cases in the control group received west medicine, zhinbiticose. The course of treatment for both groups was 8 weeks. Results: The difference in total effective rate between the two groups was significant (P<0.05). Conclusion: Antihyperlipidemic decoction has a better therapeutic effect for hyperlipemia, with a lower recurrence rate and less side effect.