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L-M(TK~-)细胞是小鼠成纤维细胞在含有5-溴脱氧脲嘧啶核苷的培液中,经90周的培养后,获得的对抗BudR的细胞株。它的特点是胸腺嘧啶核苷激酶活力的缺失。
L-M (TK~-) cells are cell lines obtained from mouse fibroblasts cultured in a 5-bromodeoxyuridine containing culture medium for 90 weeks. It is characterized by the absence of thymidine kinase activity.