肾上腺糖皮质激素长期治疗病人可引起胃溃疡,曾成为多年来的一种认识.然而,近年对32个双盲报告和18个非双盲报告共6,102例病人的研究,未能发现两者之间存在关系。动物实验发现,胃粘膜与各种肾上腺糖皮质激素的短期接触,或胃肠道外长期给予强地松龙,均未见能改变胃粘膜的渗透性。胃粘膜(Na~-K~+)ATPase是维持细 The long-term treatment of patients with adrenal glucocorticoids can cause gastric ulcers and has been a recognition for many years. However, in recent years, a total of 6,102 patients with 32 double-blind reports and 18 non-double-blind reports have failed to find any of them. There is a relationship. Animal experiments have found that short-term exposure of gastric mucosa to various adrenal corticosteroids, or long-term administration of edisonone into the gastrointestinal tract, did not alter the permeability of the gastric mucosa. Gastric mucosa (Na~-K~+) ATPase is maintained fine