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唇腭裂是颌面部最常见的先天性畸形.尽管有众多的修复方法,但相当多的患者术后不可避免的遗留术创瘢痕及面中份发育不足.作者设想在子宫内施行手术修复唇裂以避免发生以上问题。实验动物为妊娠24天的新西兰白兔.全麻下切开子宫,借助6倍外科手术显微镜于中线口角间作1mm之切口并切开齿槽突,形成全层贯通的口鼻瘘。将其中一组用9—0的尼龙缝线修复伤口,而另一组则不予缝合。对照组则只将胎兔暴露,不施行任何手术。经统计学分析,手术修复组和未修复组的术后生存率无明显差别,
Cleft lip and palate is the most common congenital malformation of the maxillofacial region.Although there are numerous repair methods, but a considerable number of patients inevitably left behind after surgery to create scars and facial hypocrisy.The authors envisaged the implementation of intraoperative uterine repair of cleft lip To avoid the above problems. The experimental animals were New Zealand white rabbits of 24 days gestation, the uterus was opened under general anesthesia, a 1 mm incision was made between the midline bicep with 6 times of surgical microscope and incision of the alveolar process to form full-thickness penetrating fistula. One of the groups repaired the wound with 9-0 nylon suture while the other group did not. The control group only exposed fetal rabbit, without any surgery. After statistical analysis, there was no significant difference in postoperative survival between surgical repair group and uncorrected group,