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刚地弓形虫是引起免疫抑制病人脑炎的重要病原体,在妊娠期如引起急性感染可导致胎儿先天性缺陷。刚地弓形虫是专性细胞内寄生虫,可侵入众多吞噬细胞和非吞噬细胞。刚地弓形虫在细胞内纳虫泡内(PV)生长、繁殖,这一特殊结构使其避免被溶酶体融合。在寄生虫和宿主细胞之间形成纳虫泡膜(PVM),该膜在虫体和细胞间调节摄食代谢、营养传递及蛋白质运输。作者应用两种
Toxoplasma gondii is an important pathogen causing encephalitis in immunosuppressed patients, causing acute infection during pregnancy can lead to congenital defects in the fetus. Toxoplasma gondii is a specialized intracellular parasites that can invade many phagocytes and non-phagocytic cells. Toxoplasma gondii grows and reproduces in the intra-nalvular vesicle (PV), a special structure that prevents it from being fused by lysosomes. An ornithobal bubble membrane (PVM) is formed between parasites and host cells that regulate feeding metabolism, nutrient delivery, and protein trafficking between parasites and cells. The author uses two kinds