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我科应用国产转移因子(TF)治疗小儿慢性乙型肝炎14例和无症状HBsAg 携带者11例.用法是每周2次,每次2ml 含4×10~3白细胞提取物,腋窝皮下注射,10周为1疗程,间歇2周,共1～2疗程.慢性乙型肝炎,治疗前14例HBsAg 及抗—HBc 均阳性,治疗后13例HBsAg 阳性(P>0.05),10例抗—HBc 阳性,2例未查;治疗前肝功能异常者9例,治疗后异常者8例(P>0.05);治疗前淋巴细胞转化试验(LBT)6例偏低,E—玫瑰花结试验(E—RFT)2例偏低,植物血凝素(PHA)皮肤试验8例弱阳性,治疗后LBT3例偏低,E—RFT3例偏低,PHA 皮肤试验5例弱阳性.1年追踪结果,复查其中8例,4例SGPT 恢复正
In our department, 14 cases of pediatric chronic hepatitis B and 11 cases of asymptomatic HBsAg carriers were treated with home-made transfer factor (TF) .It was used twice a week with 4 × 10 ~ 3 leukocyte extracts and subcutaneous axillary subcutaneous injection, 10 weeks for a course of treatment, intermittent 2 weeks, a total of 1 ~ 2 course of treatment.Chronic hepatitis B, 14 cases before treatment of HBsAg and anti-HBc were positive after treatment of 13 cases of HBsAg positive (P> 0.05), 10 cases of anti-HBc Positive in 2 cases were not detected; 9 cases of abnormal liver function before treatment, 8 cases after treatment abnormalities (P> 0.05); Pretreatment lymphocyte transformation test (LBT) 6 cases were low, E-rosette test -RFT) were low in 2 cases, 8 cases of PHA skin test were weakly positive, 3 cases of low LBT after treatment, 3 cases of E-RFT were low, 5 cases of PHA skin test were weakly positive, 1 year follow-up result, Among them, 8 cases, 4 cases of SGPT recovery positive