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目的探讨参附注射液对心肺复苏患者的影响。方法选择广州市萝岗区中医医院2012年2月-2016年4月经心肺复苏后,自主循环建立>2 h的心脏骤停患者56例为研究对象,以随机数字表法分为观察组和对照组各28例,对照组患者进行常规抢救察组在患者心肺复苏成功后应用参附注射液,对两组患者心肺复苏后血氧饱和度与平均动脉压、病死率进行观察。结果观察组心肺复苏成功后1 h、3 h、6 h、1 d血氧饱和度明显高于对照组差异有统计学意义(P<0.05)。观察组心肺复苏成功6 h之后,各时间段平均动脉压均高于对照组差异有统计学意义(P<0.05)。观察组病死率为28.57%,对照组为53.57%差异有统计学意义(P<0.05)。结论心肺复苏中应用参附注射液可提高远期平均动脉压,也能提高近期血氧饱和度,降低患者死亡率,可作为新的协同用药方案,值得推广。
Objective To investigate the effect of Shenfu injection on patients with cardiopulmonary resuscitation. Methods Luogang District Traditional Chinese Medicine Hospital of Guangzhou City from February 2012 to April 2016 After cardiopulmonary resuscitation (CPR), 56 patients with cardiac arrest who established spontaneous circulation> 2 hours were divided into observation group and control group by random number table 28 patients in each group. The patients in the control group were treated with routine rescue team. After the success of cardiopulmonary resuscitation, Shenfu injection was used to observe the blood oxygen saturation, mean arterial pressure and mortality after cardiopulmonary resuscitation in both groups. Results The oxygen saturation of 1 h, 3 h, 6 h and 1 d after cardiopulmonary resuscitation in observation group was significantly higher than that in control group (P <0.05). After 6 hours of successful CPR in observation group, mean arterial pressure in each time period was significantly higher than that in control group (P <0.05). The case fatality rate was 28.57% in the observation group and 53.57% in the control group, with significant difference (P <0.05). Conclusion The application of Shenfu injection in cardiopulmonary resuscitation can improve long-term mean arterial pressure, and also can improve the recent oxygen saturation and reduce the mortality of patients, which can be used as a new synergistic regimen and worthy of promotion.