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目的 :观察紫苏的抗凝血作用。方法 :选 SD系大鼠 2 0只 ,家兔 8只 ,应用试管法观察紫苏对实验动物凝血时间的影响 ,并与肝素作对照。结果 :紫苏与肝素有相似的抗凝血活性 ,能延长大鼠的凝血时间 ( P<0 .0 1) ;随着药液浓度的增加 ,抗凝血作用也逐渐增强。结论 :紫苏具有一定的抗凝血作用 ,其机制可能与抑制血小板功能有关
Objective : To observe the anticoagulant effect of perilla. Methods : 20 SD rats and 8 rabbits were selected. The effect of perilla on coagulation time of experimental animals was observed by test tube method and compared with heparin. Results: Perilla and heparin had similar anticoagulant activity and could prolong the clotting time of rats (P<0.01). With the increase of drug concentration, the anticoagulant effect also gradually increased. Conclusion: Perilla has a certain anticoagulant effect and its mechanism may be related to the inhibition of platelet function.