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目的 :探讨儿童感染性心内膜炎 ( IE)临床特征及影响预后的因素。方法 :对 2 3例 IE患儿的所有资料进行回顾性分析。结果 :2 3例 IE患儿治愈 7例 ,死亡 3例 ,其余均好转或无效自动出院。持续发热 ,气促、心慌、咳嗽为其主要临床表现。血培养阳性占 69.0 %。其中金葡菌 1 0例 ,占 62 .5 % ,超声心动图检查发现赘生物 1 7例 ;有赘生物及基础心脏病组病死率为 1 7.6% ( 3/1 7) ,无赘生及及基础心脏病组无死亡 ;血培养阳性组病死率为 1 8.7%( 3/1 6) ,血培养阴性组无死亡。结论 :IE的临床症状为持续发热、气促、心慌、咳嗽 ;金葡菌感染占首位。预后与赘生物存在 ,基础心脏病存在 ,血培养阳性 ,栓塞以及起病急骤有关
Objective: To investigate the clinical characteristics of children with infective endocarditis (IE) and prognostic factors. Methods: All the data of 23 cases of children with IE were analyzed retrospectively. Results: Twenty-three children with IE were cured in 7 cases and 3 died. The rest were either improved or ineffectively discharged. Continuous fever, shortness of breath, palpitation, cough as its main clinical manifestations. Blood culture positive accounted for 69.0%. Staphylococcus aureus in which 10 cases, accounting for 62.5%, echocardiography found neoplasm 17 cases; with neoplasms and basic heart disease group mortality was 7.6% (3/17), non-neoplastic and And no death in the basic heart disease group. The mortality rate in the positive blood culture group was 18.7% (3/16). There was no death in the negative blood culture group. Conclusion: IE clinical symptoms of persistent fever, shortness of breath, palpitation, cough; Staphylococcus aureus infection in the first place. Prognosis and the presence of neoplasms, the existence of basic heart disease, blood culture positive, embolism and sudden onset