论文部分内容阅读
为探讨新生儿非感染性疾病免疫状态,本文测定了45例新生儿非感染性疾病患儿多项免疫指标。结果显示:新生儿硬肿症患儿血 IL-2水平、NK细胞活性明显低于对照组及其它患儿(P<0.01),SIL-2R水平及T_s抑制率则明显增高(P<0.01),所有患儿血清Ig水平均无明显变化(P>0.05)。IL-2水平与NK细胞活性及T_s抑制率与 SIL-2R水平间均呈正相关( P <0. 01),IL-2水平与 SIL-2R水平、T_s抑制率与 IL-2水平及 NK细胞活性、SIL-2R水平与 NK细胞活性间均呈负相关( P<0.01)。提示,新生儿硬肿症患儿细胞免疫功能降低,此可能是其易并发感染的原因之一。
In order to explore the immune status of neonatal noninfectious diseases, we measured a number of immunosuppressive markers in 45 neonates with noninfectious diseases. The results showed that the levels of IL-2 and NK cells in children with scleredema were significantly lower than those in control group and other children (P <0.01), and the levels of SIL-2R and T_s were significantly increased (P < 0.01), all children had no significant changes in serum Ig levels (P> 0.05). There was a positive correlation between IL-2 level, NK cell activity and T_s inhibition rate and SIL-2R level (P <0.01), IL-2 level and SIL-2R level, T_s inhibition rate and IL-2 level and NK cell There was a negative correlation between activity and SIL-2R level and NK cell activity (P <0.01). Tip, neonatal scleredemia in children with decreased cellular immunity, which may be one of the reasons for its easy to complicated infection.