迄今尚无理想的感染人乙型肝炎病毒(HBV)的动物模型可供实验研究之用。虽然曾在黑猩猩、长臂猿、翠猴、狒狒和恒河猴等多种非人灵长之类中发现自然感染的例子,并能在黑猩猩、恒河猴和平顶猴等实现人工感染,其中在黑猩猩的实验感染成功率高,接种后感染指标存在持续时间较长,但此种动物难以获得,更不可能复制 To date, there is no ideal animal model for infecting people with hepatitis B virus (HBV) for experimental research. Although natural infections have been found in a variety of non-human primate species such as chimpanzees, gibbons, crested monkey, baboon and rhesus monkeys, artificial infection can also be achieved in chimpanzees, rhesus monkeys and flat-headed monkeys, Of the high success rate of experimental infection, infection indicators after inoculation there is a longer duration, but this animal is difficult to obtain, but more impossible to copy