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目的探讨山东省沂蒙山区≥95岁老年人的长寿因素,为促进人群健康长寿提供科学依据。方法采用问卷调查及成组病例-对照研究设计,对650名长寿老年人及571名非长寿老年人进行调查,采用非条件Logistic回归分析筛选长寿的影响因素,并通过计算长寿的遗传度,分析长寿的遗传倾向。结果与长寿有关的正向因素有父亲高寿(OR=1.929,95%CI=1.053~3.531)、生育子女数较多(OR=1.319,95%CI=1.209~1.438)、性格外向(OR=3.204,95%CI=1.446~7.101)、健康很少生病(OR=2.832,95%CI=1.975~4.060),与长寿有关的负向因素有兄弟姊妹较多(OR=0.317,95%CI=0.509~0.749)、饮酒(OR=0.996,95%CI=0.994~0.999);长寿遗传度为21.98%。结论长寿是多因子性状,遗传因素起重要作用,良好的环境和健康的生活习惯与行为方式也有利于长寿。
Objective To investigate the longevity of ≥95-year-old in Yimeng Mountain, Shandong Province, and to provide a scientific basis for promoting the health and longevity of the population. Methods A total of 650 longevity elderly and 571 non-longevous elderly were investigated by questionnaire and group case-control study. Non-conditional logistic regression analysis was used to screen for the influencing factors of longevity, and by calculating the longevity of the genetic analysis, Longevity genetic predisposition. Results The positive factors related to longevity were father’s longevity (OR = 1.929, 95% CI = 1.053-3.531), more children of childbirth (OR = 1.319, 95% CI = 1.209-1.438) , 95% CI = 1.446-7.101) .Shealth was seldom sick (OR = 2.832, 95% CI = 1.975-4.060). There were more siblings with negative factors related to longevity (OR = 0.317, 95% CI = 0.509 ~ 0.749), drinking alcohol (OR = 0.996, 95% CI = 0.994-0.999); the longevity geneticity was 21.98%. Conclusion Longevity is a multifactorial trait, genetic factors play an important role, good environment and healthy lifestyle and behavior are also conducive to longevity.