【摘 要】
：
A rapid and practical method for direct detection of lisinopril in anion exchange chromatography (AEC) has been developed with integrated pulsed amperometric de
【机 构】
：
School of Chemistry and Chemical Engineering,Zhe Jiang Academy of Traditional Chinese Medicine,Colle
论文部分内容阅读
A rapid and practical method for direct detection of lisinopril in anion exchange chromatography (AEC) has been developed with integrated pulsed amperometric detection (IPAD).Dionex AS18 (250 mm × 2 mm) and AG18 (50 mm × 2 mm) columns and 40 mmol/L NaOH solution were used for separation.Multi-step potential waveform parameters were optimized to maximize the signal-to-noise ratio (S/N).Utilizing the optimized waveform,the repeatability (intra-day) precision and intermediate (inter-day)precision were obtained with relative standard deviation (RSD) of 0.74,0.93,respectively.The limit of quantification (LOQ) and limit of detection (LOD) were found to be 0.37,0.12 ng/mL,respectively,with the correlation coefficient of 0.9998 over concentration range 0.01-1 μg/mL.The present method was successfully applied to the determination of lisinopril in human plasma.The recoveries of plasma sample spiked by 0.2 μ g/mL,0.8 μg/mL lisinopril were 98.31-103.23％ with RSD of 1.41％,0.61％,respectively.
其他文献
目的 探讨心理干预对冠心病介入手术患者心理状态及生活质量的影响.方法 选取2009年11月至2012年11月在我院心血管内科住院治疗的冠心病患者80例,随机分为观察组和对照组各40
目的 探讨对妊娠期合并乳腺癌患者采取心理护理达到的临床效果.方法 选取2010年2月至2013年2月在我院接受治疗的妊娠期合并乳腺癌患者30例,对所有患者均采取心理护理,对比治
目的 观察并分析运用心理护理联合康复技术对中风患者恢复自理能力和精神状态的临床效果.方法 近些年来,本院共收治脑中风后遗症患者106例,在对患者进行护理的过程中,运用针
目的 探讨护理干预对风湿性心脏病患者焦虑心理的影响.方法 将80例风湿性心脏病患者随机分为干预组和对照组,各40例,对照组采用常规护理,干预组在此基础上给予专项护理干预,
目的：调查乳腺癌患者家属生活质量及其影响因素。方法采用问卷调查方法对86名乳腺癌患者家属进行横断面调查，了解患者家属的一般资料，并采用癌症患者照顾者生活质量调查表（CQOL）评
目的：探讨造口志愿者在结肠灌洗临床推广中的应用效果。方法造口志愿者协助造口治疗师，通过在造口联谊会上现身讲解、造口门诊宣教等方式宣传结肠造口灌洗知识，与造口治疗师一起
《史记》作为西汉时期一部重要典籍,反映了这一时期语言发展的真实面貌,是我们研究汉语史的重要资料。本文以《史记》为研究对象,对其连接副词的使用情况进行考察和分析,试图
根据投入产出表中对增加值系数的描述,提出了四种增加值弹性指标来判定关键部门,弹性指标考虑部门规模,更具有可比性,且用最终使用变动影响的GDP及劳动者报酬、税收、营业盈
N-Arylation of a wide variety of amines with phenylboronic acid catalyzed by copper acetate under 20%aqueous solution of n-Bu_4NOH was accomplished in good to e
Nowadays,more and more users share real-time news and information in micro-blogging communities such as Twitter,Tumblr or Plurk.In these sites,information is sh