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近年来对肿瘤基因及其产物的检测已和临床上肿瘤分类、发病机制、恶性程度、转移以及预后估计密切结合起来。p53基因的突变与丢失和EGFR（epidermalgrowthfactorrecep－tor，表皮生长因于受体）基因扩增是胶质瘤发生发展过程中常见的分子改变。本文应用免疫组化方法检测脑星形?
In recent years, the detection of tumor genes and their products has been closely integrated with clinical tumor classification, pathogenesis, malignancy, metastasis, and prognosis estimation. Mutation and loss of p53 gene and amplification of EGFR (epidermal growth factor receptor) gene are common molecular changes in the development of glioma. This article applies immunohistochemistry to detect brain stars?