RNA-seq reveals the critical role of Csp A in regulating Brucella melitensis metabolism and virulenc

来源 :中国科学:生命科学英文版 | 被引量 : 0次 | 上传用户:xufei777
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Brucella melitensis is a facultative intracellular bacterium that replicates within macrophages. The ability of Brucella to survive and multiply in the hostile environment of host macrophages is essential for its virulence. The cold shock protein Csp A pl
其他文献
Mutations of integrin-interacting protein Kindlin-1 cause Kindler syndrome and deregulation of Kindlin-1 is implicated in human cancers. The Kindlin-1-related d
期刊
<正>Genomes have been studied by biologists for decades with a goal to decipher the origin,evolution,and nature of life on earth.These studies often rely on gen
The posttranscriptional addition of nontemplated nucleotides to the 3′ ends of RNA molecules can have a significant impact on their stability and biological fu
期刊
Pluripotent 干细胞(PSC ) 是能在身体区分进房间的任何类型的房间,因此在房间代替治疗和织物 / 器官工程的再生药有珍贵诺言。PSC 能被 epigenetic reprogramming 从体的房间
Synthetic biology is an interdisciplinary field that takes top-down approaches to understand and engineer biological systems through design-build-test cycles. A
Ryanodine receptors(Ry Rs) are the calcium release channels of sarcoplasmic reticulum(SR) that provide the majority of calcium ions(Ca2+) necessary to induce co
Like the type I interferons(IFNs),the recently discovered cytokine IFN-λ displays antiviral,antiproliferative,and proapoptotic activities,mediated by a heterod
Our previous study demonstrated that a chloroplast co-chaperonin 20(CPN20),one of the interaction partners of the magnesium-protoporphyrin IX chelatase H subuni