Fas介导的细胞凋亡对细胞的增殖调控起重要作用。Fas受体与其相应配体结合后 ,通过蛋白死亡区的相互作用激活一系列信号蛋白及蛋白酶 ,引起多种底物的降解 ,导致细胞出现凋亡的生化及形态学改变。 Fas-mediated apoptosis plays an important role in the regulation of cell proliferation. Fas receptors bind to their corresponding ligands and activate a series of signaling proteins and proteases through the interaction of protein death regions, causing degradation of various substrates and resulting in the biochemical and morphological changes of apoptosis.