女性发生胆囊结石的可能性比男性多2～3倍,经产妇的胆固醇性胆结石病患病率尤其高。而在年轻妇女中较多处于慢性缺铁状态,这种关系提示在妇女中胆固醇胆结石的形成和慢性缺铁之间有着一种联系。 为检验缺铁可能改变肝的胆固醇代谢和促进胆固醇性胆结石形成的假设,进行了研究。 材料与方法:40只成年雄性草原犬鼠分为 The incidence of gallstone in women than men 2 to 3 times more, the prevalence of maternal cholesterol gallstone disease is particularly high. In young women, however, they are at a chronic state of chronic iron deficiency, a link that suggests a link between the development of cholesterol gallstones and chronic iron deficiency in women. To examine the hypothesis that iron deficiency may alter hepatic cholesterol metabolism and promote cholesterol gallstone formation, a study was conducted. MATERIALS AND METHODS: Forty adult male prairie dogs were divided into two groups