Plummer和同事们在本期《New Engl J Med》上发表的文章引起各方注意到微小病毒(Parvovirus)在感染人体致病中的作用。一段时间以来,虽然对动物的微小病毒感染已有认识,但近十年来才对此病毒与人类疾病的关系有明确的了解。在一系列的迹象中,最初的认识是来自一次偶然的发现。在七十年代中期,当评价测定乙型肝炎表面抗原的新方法时,在对流免疫电泳法测定时,发现一些单位血液表现出“反应性”,但后来用更敏感的方法测定时,对抗原无反应。以后应用精密的电 Plummer and colleagues in this issue of the article “New Engl J Med” have drawn the attention of the parties to the role of Parvovirus in the pathogenesis of human infections. Although animal puppies have been known for some time now, the relationship between the virus and human diseases has not been clearly understood in the recent decade. In a series of signs, the initial recognition came from a fortuitous discovery. In the mid-1970s when evaluating new methods of determining Hepatitis B surface antigen, some units of blood were found to be “reactive” when measured by convective immuno-electrophoresis, but later on with more sensitive methods, No reaction. After the application of sophisticated electricity