国内报道307例慢粒急变中,嗜碱细胞型共5例,其疗效差,病程短,多死于颅内出血.我们遇到1例,报道如下:病例介绍女,32岁,农民,于1934年12月19日因右下肢疼痛、畏寒发热7天住院,确诊为慢粒,用马利蓝治疗完全缓解出院.1985年6月、9月及1986年3月患者因大量呕血及黑便三次住院,住院期间共查外周血18次,嗜碱粒细胞为2～5%,缓解期三次查骨髓中嗜碱粒细胞2～6.4%,大多为 China reported 307 cases of acute blast crisis, basophil type in 5 cases, the curative effect is poor, short course, died of intracranial hemorrhage .We encountered 1 case, reported as follows: Case description Female, 32 years old, farmer, in 1934 December 19, due to right lower extremity pain, chills and fever 7 days hospitalized, diagnosed as CML, with Marilyn blue cure completely discharged .In June 1985, September and March 1986 patients due to massive vomiting and melena Three hospitalizations during hospitalization were investigated 18 times peripheral blood, basophils, 2 to 5%, three times during the remission check bone marrow basophils 2 to 6.4%, mostly