两种硫辛酸对映体对胚胎体外发育的影响

来源 :兰州大学学报(医学版) | 被引量 : 0次 | 上传用户:lvsby2009
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目的探讨(R)-硫辛酸和(S)-硫辛酸对胚胎体外发育的影响。方法解冻复苏卵裂期胚胎,分别在含不同浓度(R)-硫辛酸和(S)-硫辛酸的GⅡ培养基微滴中培养,观察各组的桑胚率、致密化率、囊胚率和优质囊胚率。结果硫辛酸可提高胚胎体外发育率,(R)-硫辛酸浓度10×10^-9mol/m^3组桑胚率、致密化率、囊胚率和优质囊胚率分别达到了59.2%,55.1%,49.0%和54.2%,均高于其他浓度组(P〈0.01)。(R)-硫辛酸浓度10×10^-9mol/m^3组的桑胚率、致密化率和优质胚胎
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