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英国一项研究表明,与标准和肝素浸渍中心静脉导管相比,抗生素浸渍导管可显著降低血流感染风险。广泛应用抗生素浸渍中心静脉导管可预防儿科重症监护室的血流感染。论文3月3日在线发表于《柳叶刀》(Lancet)杂志。研究共纳入1485例儿科监护室患儿,随机给予标准、抗生素浸渍或肝素浸渍中心静脉导管。主要转归为,置管后48小时至导管移除后48小时期间,至首次血流感染发生时间。结果显示,标准、抗生素浸渍和肝素浸渍中心静脉导管组相应的血流感
A British study showed that antibiotic-impregnated catheters significantly reduced the risk of bloodstream infections compared to standard and heparin-infused central venous catheters. Extensive use of antibiotics to impregnate central venous catheters prevents bloodstream infections in pediatric intensive care units. Papers online March 3, “Lancet” (Lancet) magazine. A total of 1485 pediatric intensive care units were enrolled in this study. Patients were randomized to standard antibiotic impregnation or heparin impregnated central venous catheters. The main outcome was 48 hours after catheterization to 48 hours after catheter removal until the time of initial bloodstream infection. The results showed that the standard, antibiotic impregnation and heparin impregnated central venous catheter group corresponding blood flu