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鉴于19-羟-前列腺素(19-OH-PGs)是人或灵长类动物精液中前列腺素的主要成分。本人观察人工合成的19-OH-PGs(两种异构体19(R)-OH-PGE_2、19(S)-OH-PGE_2)和19-OH-PGFS(两种异构体19(R)-OH-PGF_(2a)、19(S)-OH-PG-F_(2a))对生殖道肌肉活性的影响,并与PGE_2和PGF_(2a)比较。作者对8只没交配的新西兰兔和两只中期怀孕的恒河猴进行在体实验。兔实验是用塑胶微型气球放在输卵管邻近峡部记录腔内压力变化。橡胶微型气球置于子宫腔内记录子宫活性。猴子宫活性测定
Given that 19-OH-PGs are the major component of prostaglandins in human or primate semen. I observed both the synthetic 19-OH-PGs (the two isoforms 19 (R) -OH-PGE 2, 19 (S) -OH-PGE 2) -OH-PGF_ (2a), 19 (S) -OH-PG-F_ (2a) on reproductive tract muscle activity was compared with that of PGE_2 and PGF_ (2a). The authors conducted in-vivo experiments on eight unmatched New Zealand rabbits and two mid-pregnant rhesus monkeys. Rabbit experiment is to use plastic mini balloon placed in the fallopian tube near the isthmus to record changes in intracavity pressure. Rubber mini-balloon placed in the uterine cavity recording uterine activity. Monkey uterus activity assay