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血管内皮生长因子(vasculaar endothelialgrowth factor,VEGF)是一类能促使血管增生和增加血管渗透性的糖蛋白。本研究目的旨在评价人正常和炎性牙髓中的VEGF和微血管密度(mi-crovessel density,MVD)的关系。 材料和方法 正常牙髓来源于拔除的下颌智齿,炎性牙髓来源于不可复性牙髓炎患牙,两组各25个标本。采用APAAP法免疫组化染色技术进行研究。①评价血管、炎性细胞(主要为中性粒细胞、淋巴细胞和浆细胞)和基质细胞VEGF的表达。依据VEGF阳性细胞百分比和阳性细胞染色密度评
Vascular endothelial growth factor (VEGF) is a type of glycoprotein that promotes vascular proliferation and increases vascular permeability. The aim of this study was to evaluate the relationship between VEGF and micro-crovessel density (MVD) in human normal and inflammatory pulp. Materials and Methods Normal dental pulp derived from extracted mandibular wisdom teeth, inflammatory pulp derived from irreversible pulpitis teeth, two groups of 25 specimens. APAAP immunohistochemical staining technique was used to study. ① Evaluation of vascular, inflammatory cells (mainly neutrophils, lymphocytes and plasma cells) and stromal cells VEGF expression. According to the percentage of VEGF-positive cells and positive cell staining density