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脑梗塞超过一定时间后,恢复血液再灌流可加重病情,使缺血进一步发展并达到高峰.现在证实脑梗塞再灌流性损害,是自由基连锁反应激化所造成的,所以,清除自由基,切断自由基连锁反应,可能是治疗脑梗塞的首要条件.我们自1992年10月始,对62例急性脑梗塞病人随机分为清除自由基治疗与传统治疗两组进行疗效对比.1 临床资料1.1 一般资料:62例患者均按1986年中华医学会第二次全国脑血管病学术会制定的各类脑血管病诊断要点确诊,并经CT证实.年龄最小39岁,最大84岁.梗塞部位在底节和侧脑室体旁48例,内囊后支8例,小脑梗塞3例,颞顶枕叶大面积梗塞3例.病程在7天以内,分为清除自由基治疗组和传统治疗组各31例.治疗前均查CT、心电图、血糖、血脂.
After a certain period of cerebral infarction, the restoration of blood reperfusion can aggravate the condition, the further development of ischemia and reached its peak now confirmed that cerebral infarction reperfusion injury is caused by the radical chain reaction intensification, so clear free radicals, cut off Free radical chain reaction may be the first condition for the treatment of cerebral infarction.We started from October 1992, 62 patients with acute cerebral infarction were randomly divided into two groups of free radical scavenging therapy and traditional treatment efficacy comparison.1 Clinical data 1.1 General Data: 62 patients were diagnosed according to the diagnostic points of various cerebrovascular diseases formulated by the Second National Cerebrovascular Disease Academic Society of China in 1986 and confirmed by CT, the youngest was 39 years old and the oldest was 84 years old. Section and the lateral ventricle in 48 cases, 8 cases of posterior internal capsule, cerebellar infarction in 3 cases, temporal topoccipital lobe large infarction in 3 cases .During the course of 7 days, divided into free radical therapy group and the traditional treatment group of 31 Cases before treatment were checked CT, ECG, blood glucose, blood lipids.