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目的:探讨少、弱精子症患者精液处理前前向运动精子总数(TPMS)对宫腔内人工授精(IUI)妊娠率的影响。方法:回顾性分析338对因少、弱精子症来该院生殖科行夫精人工授精(AIH)的夫妇共计465个周期的临床资料。按照精液样本(a+b)级精子总数将患者分成三组:A组(<10×106)、B组(10×106~20×106)、C组(>20×106),比较这三组的前向运动精子回收率和周期临床妊娠率。结果:三组前向运动精子回收率分别为(44.88±7.56)%、(45.50±6.82)%、(42.52±10.07)%,三组比较差异无统计学意义(P>0.05);三组周期临床妊娠率分别为8.06%、15.72%、16.48%,A组周期妊娠率明显低于B、C两组,差异有统计学意义(P<0.05),B、C两组比较差异无统计学意义(P>0.05)。结论:处理前TPMS是AIH选择和评估预后的重要参考指标。
Objective: To investigate the effect of TPMS on pregnancy rate of intrauterine insemination (IUI) in semen of oligoastatic and asthenospermia patients. Methods: A retrospective analysis of 338 pairs of less, weak sperm disease to the hospital reproductive line sperm husbandry artificial insemination (AIH) couples a total of 465 cycles of clinical data. Patients were divided into three groups according to the total number of sperm samples (a + b): group A (<10 × 106), group B (10 × 106 ~ 20 × 106) and group C (> 20 × 106) Group forward motility sperm recovery and cycle clinical pregnancy rate. Results: The recovery rates of forward motility sperm among the three groups were (44.88 ± 7.56)%, (45.50 ± 6.82)% and (42.52 ± 10.07)%, respectively. There was no significant difference between the three groups (P> 0.05) The clinical pregnancy rates were 8.06%, 15.72% and 16.48% respectively. The pregnancy rate in group A was significantly lower than that in group B and C (P <0.05), but there was no significant difference between groups B and C (P> 0.05). Conclusion: TPMS before treatment is an important reference index for AIH selection and prognosis evaluation.