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目的探讨瑞芬太尼在婴幼儿快通道心脏麻醉中的应用效果,为临床治疗提供理论依据。方法将70例先天性心脏病患儿随机分为观察组与对照组各35例,对照组给予芬太尼麻醉,观察组给予瑞芬太尼麻醉,比较两组患儿清醒时间、拔管时间以及不同时间点血流动力学参数值。结果两组患儿麻醉诱导前平均动脉压、舒张压、收缩压、心率比较差异无统计学意义(P>0.05)。麻醉诱导后、插管后、切皮后、体循环前平均动脉压、舒张压、收缩压、心率均下降,与诱导前比较差异有统计学意义(P<0.05),组间比较则差异无统计学意义(P>0.05)。观察组患儿清醒时间、拔管时间、拔管时间>6h率、ICU入住时间均低于对照组,差异有统计学意义(P<0.05)。结论在婴幼儿快通道心脏麻醉中,应用瑞芬太尼与芬太尼均可以保持患儿术中血流动力学参数稳定,但瑞芬太尼减少了拔管时间及清醒时间,缩短了留观时间,更适宜用于婴幼儿快通道心脏麻醉。
Objective To explore the effect of remifentanil in fast-track cardiac anesthesia in infants and young children, and to provide a theoretical basis for clinical treatment. Methods Seventy children with congenital heart disease were randomly divided into observation group and control group with 35 cases each. The control group was given fentanyl anesthesia, and the observation group was given remifentanil anesthesia. The awake time, extubation time And hemodynamic parameters at different time points. Results There was no significant difference in mean arterial pressure, diastolic blood pressure, systolic blood pressure and heart rate before anesthesia induction in both groups (P> 0.05). After intubation and intubation, mean arterial pressure, diastolic blood pressure, systolic blood pressure and heart rate before intubation after intubation were significantly different from those before induction (P <0.05), but there was no statistical difference between the two groups Significance (P> 0.05). The awake time, extubation time, extubation time> 6h rate and ICU stay time in the observation group were all lower than those in the control group, the difference was statistically significant (P <0.05). CONCLUSION: Remifentanil and fentanyl can keep the intraoperative hemodynamic parameters stable in infant fast-track cardiac anesthesia, but remifentanil reduces extubation time and awake time and shortens the stay View time, more suitable for infant fast-track cardiac anesthesia.