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目的探讨锥切治疗早期宫颈癌后肿瘤及妊娠结局。方法 40例早期宫颈癌有生育要求的患者作为研究对象,均采用锥切治疗,回顾肿瘤及妊娠结局资料。结果本组术前病理检查,宫颈癌ⅠA1期18例,宫颈上皮内瘤变(CIN)22例。术后病理证实为鳞状细胞癌。行锥切治疗,成功率为97.5%。12例积极尝试妊娠,妊娠成功6例,妊娠时间平均为术后10个月,其中足月分娩3例,自然流产和药物流产各1例,早孕胎停育1例。结论宫颈癌近年发病年龄渐趋年轻化,加之筛查手段的提高和普查力度的重视,早期宫颈癌检出率明显增加。针对宫颈癌ⅠA1期患者,采用锥切治疗有较高安全性,妊娠结局理想,复发率低,故临床医师需重视手术适应证的把握,以最大程度改善预后,保障患者生存质量。
Objective To investigate the effect of conization on early stage cervical cancer and pregnancy outcome. Methods Forty patients with early stage cervical cancer who had fertility requirements were enrolled in this study. All cases were treated with conization, and the tumor and pregnancy outcomes were reviewed. Results This group of preoperative pathological examination, cervical cancer Ⅰ A1 18 cases of cervical intraepithelial neoplasia (CIN) in 22 cases. Postoperative pathology confirmed as squamous cell carcinoma. Cone incision treatment, the success rate was 97.5%. 12 cases of positive pregnancy, 6 cases of successful pregnancy, the average pregnancy time of 10 months after operation, of which 3 cases of full-term delivery, spontaneous abortion and medical abortion in each one case, one case of early pregnancy and childbirth. Conclusion Cervical cancer in recent years, the age of getting younger and younger, combined with the means of screening and census efforts to pay attention to the early detection rate of cervical cancer increased significantly. Cervical cancer patients with stage Ⅰ A1, the use of conization cut has a higher safety, pregnancy outcome is ideal, the recurrence rate is low, so clinicians should pay attention to the indications of surgery to maximize prognosis and ensure the quality of life of patients.