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目的探讨乳腺纤维瘤切除术围术期应用预防性抗菌药物的成本-效果。方法选取2011年8月至2013年8月我院接收的乳腺纤维瘤切除术100例患者的围术期预防性抗菌药物的使用资料,按用药不同分为A、B两组并进行回顾性分析。结果用药时间≤24 h,A组有效率为92.0%,B组为91.3%;用药时间>24 h,A组有效率为96.0%,B组为92.6%;且两组患者术前术后身体情况比较,差异均无统计学意义(P>0.05);A组药物价格明显低于B组,差异有统计学意义(P<0.05)。结论乳腺纤维瘤切除术后24 h便可停止预防性使用抗菌药物,且头孢唑林钠成本更为低廉。
Objective To investigate the cost-effectiveness of prophylactic antibacterials in the perioperative period of resecting breast fibroids. Methods The data of perioperative prophylactic antibacterials in 100 cases of breast fibroactomy received in our hospital from August 2011 to August 2013 were divided into two groups according to different drugs and analyzed retrospectively . Results The effective rate of group A was 92.0%, group B was 91.3%, group A was 96.0%, group B was 92.6%, and group B was 91.3% There was no significant difference between the two groups (P> 0.05). The price of drug in group A was significantly lower than that in group B (P <0.05). Conclusion The prophylactic use of antibiotics can be stopped 24 hours after the resection of breast fibroids, and the cost of cefazolin sodium is lower.