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以22例小面积烧伤患者为研究对象,通过 CES-D 抑郁量表的筛选,将患者分为烧伤伴抑郁症状组(A 组)和烧伤无抑郁症状组(B 组),并对两组患者进行汉密顿抑郁量表(HAMD)评分、血浆β-内啡肽(BEP)和淋转功能检测。结果表明,A 组的 HAMD 评分及血浆 BEP 水平较 B 组明显升高,而 A 组的淋转功能则明显低于 B 组。患者的 HAMD 评分与血浆 BEP 水平存在显著的正相关,而血浆 BEP 水平则与淋转功能呈显著的负相关。研究提示,烧伤病人的抑郁症状作为心理应激的一种表现形式,对淋巴细胞功能有抑制作用。
Twenty-two patients with small area burn were enrolled in this study. Patients were divided into two groups according to the scale of CES-D depression: burn-associated depression (group A) and burn-free depression (group B) HAMD score, plasma β-endorphin (BEP) and lymph node metastasis were measured. The results showed that the HAMD score and plasma BEP level in group A were significantly higher than those in group B, while the leaching function in group A was significantly lower than that in group B. There was a significant positive correlation between HAMD score and plasma BEP level, while plasma BEP level was negatively correlated with lymph node metastasis. Research suggests that the symptoms of depression in burn patients as a manifestation of psychological stress, have an inhibitory effect on lymphocyte function.