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目的:探讨低分子肝素在治疗急性脑梗死中的作用和意义。方法:以我院2011年1月至2012年7月收治的82例急性脑梗死患者为研究对象,将其随机分为对照组和观察组,两组患者均行基础治疗与护理,观察组患者使用低分子肝素皮下注射,对照组患者使用低分子左旋糖酐加复方丹参静脉滴注,比较两组患者在治疗1周后血液流变学指标、生活能力恢复情况及研究前后C反应蛋白之间的差异。结果:经过1周的治疗,观察组患者在血浆黏度、纤维蛋白原及红细胞压积上皆低于对照组,在认知反应能力和言语表达能力上优于对照组,其差异皆有统计学意义(P<0.05)。在治疗前,两组患者血浆中的C反应蛋白含量无显著差异,但在治疗后,观察组患者的C反应蛋白低于对照组,其差异有统计学意义(P<0.05)。结论:低分子肝素可以有效纠正急性脑梗死后患者的血液高凝状态,有抗炎作用,对提高治疗效果,促进患者恢复有积极意义。
Objective: To investigate the role and significance of low molecular weight heparin in the treatment of acute cerebral infarction. Methods: A total of 82 patients with acute cerebral infarction admitted from January 2011 to July 2012 in our hospital were randomly divided into control group and observation group. Both groups received basic treatment and nursing. Patients in observation group Using low molecular weight heparin subcutaneous injection, the control group patients with low molecular weight levofloxacin plus compound Salvia intravenous drip, compared two groups of patients after 1 week of treatment of hemorheological parameters, viability recovery and before and after C-reactive protein The difference. Results: After a week of treatment, the observation group patients in the plasma viscosity, fibrinogen and hematocrit were lower than the control group, cognitive ability and verbal expression superior to the control group, the differences were statistically Significance (P <0.05). Before treatment, there was no significant difference in plasma C-reactive protein between the two groups. However, the C-reactive protein in the observation group was lower than that in the control group after treatment (P <0.05). Conclusion: Low molecular weight heparin can effectively correct the state of blood hypercoagulability in patients with acute cerebral infarction and has anti-inflammatory effect, which has positive significance for improving the therapeutic effect and promoting the recovery of patients.