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目的探讨丙泊酚在人工流产术中临床应用效果及安全性。方法自愿行人工流产者400例,随机分成用丙泊酚静脉麻醉的实验组200例,不采用任何干预措施的对照组200例,术中常规使用心电监护仪监测,观察手术镇痛效果、宫颈松弛情况、出血量及术中术后不良反应。结果实验组镇痛效果明显,与对照组相比差异有统计学意义(P<0.05);宫颈松弛与对照组相比差异有统计学意义(P<0.05);出血量与对照组相比差异无统计学意义(P>0.05);实验组术后血压、心率、呼吸无明显变化。结论丙泊酚用于人工流产术麻醉是一种安全可靠、有效、不良反应少的麻醉方法,适用于门诊无痛人工流产术。
Objective To investigate the clinical effect and safety of propofol in artificial abortion. Methods A total of 400 voluntary induced abortion cases were randomly divided into two groups: experimental group (n = 200) with propofol anesthesia; control group (n = 200) without any intervention; routine monitoring with ECG monitor during operation; Cervical relaxation, bleeding and postoperative adverse reactions. Results The analgesic effect of the experimental group was obvious, and there was significant difference compared with the control group (P <0.05). There was significant difference between the cervical relaxation and the control group (P <0.05) No statistical significance (P> 0.05); no significant changes in blood pressure, heart rate and respiration in the experimental group. Conclusion Propofol anesthesia for abortion is a safe, effective and less adverse anesthesia method, suitable for out-patient painless abortion.